Caryophyllene is a bicyclic sesquiterprene found in clove (3.56%), rosemary (up to 8.3%), oregano (4.9%), black pepper (7.29%), and possibly cedarwood atlas. (1) ß-carophyllene is the major sesquiterpene found in pepper essential oil (2).It may have some anaesthetic effect, as found in this study. “In this work we studied the local anaesthetic activity of β-caryophyllene, one of the…