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Chemistry of skin: Natural moisturizing factor (NMF)

January 15, 2024March 12, 2010 by Susan Barclay-Nichols

Natural moisturizing factor (NMF) is found within the corneocytes, and makes up 20% to 30% of the dry weight of the stratum corneum. It consists of amino acids (40%), sodium PCA (12%), lactate (12%), urea (7%), ions (18.5%), sugars (like glycerol – 8.5%), and a few other things. These are water soluble humectants (meaning they…

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