Preservatives: Inactivation by cellulose derivatives

There’s one more thing to consider when using our preservatives – inactivation by cellulose derivatives! In this study, various cellulose derivatives were tested with various preservatives to see which ones retained their efficacy. Here’s the list… Methylcellulose reduced paraben efficacy. Methylcellulose, sodium carboxymethylcellulose, and hydroxypropylmethylcellulose all reduced phenoxyethanol efficacy. Gelatin reduced paraben efficacy. Polyvinylpyrrolidone (PVP)...

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Preservatives: Inactivation of preservatives by pigments

I bet you never though your pigments could have such an effect on your preservative system – but they do! As with the inactivation of preservatives by non-ionic ingredients, this problem is one for the parabens. If you make mineral make-up, this really relates to you! (Click here to read the entire study.) Inorganic pigments...

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Preservatives: Inactivation of preservatives by non-ionic ingredients

I mentioned in the parabens post that some preservatives – mostly the parabens – can be inactivated by non-ionic ingredients, including some of the fatty alcohols (like cetearyl alcohol), fatty acids, esters, and polysorbates, when they’re used as emulsifiers (using the HLB system). The paraben based preservatives include Phenonip, Liquipar, and Germaben II, and the...

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Preservative: Cosmocil CQ

Cosmocil CQ is a really novel preservative, relying upon polyhexamethylene biguanide (PHMB) as the preservative, which is neither a formaldehyde releaser nor a paraben based product. The INCI is polyaminopropyl biguanide. It’s both a bacteriostatic and bactericidal preservative that should be combined with a fungicide like one of the parabens, potassium sorbate, or sodium benzoate (one...

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Preservatives: Hurdle technology

I’ve seen this term thrown around when it comes to preservatives, but what exactly is hurdle technology? It’s basically the concept of using “different bacteria inhibiting or bacteria killing factors to achieve a safe product with an optimal shelf life”. In other words, it’s about combining different preservatives at lower levels to achieve good preservation...

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