Chemistry of skin: Stratum corneum lipids (updated)

If you’ve just joined us, please check out this post on the chemistry of your skin before reading onwards… If we think of the corneocytes in the stratum corneum as “bricks”, then the stratum corneum lipids are the mortar. (The water soluble natural moisturizing factor is found inside the corneocytes; the lipid soluble stratum corneum...

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Chemistry of skin: Natural moisturizing factor (NMF)

Natural moisturizing factor (NMF) is found within the corneocytes, and makes up 20% to 30% of the dry weight of the stratum corneum. It consists of amino acids (40%), sodium PCA (12%), lactate (12%), urea (7%), ions (18.5%), sugars (like glycerol – 8.5%), and a few other things. These are water soluble humectants (meaning they...

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Science-y thought for the day…

I’m always fascinated by what we don’t know about stuff. We can put a man on the moon and create robots and describe in minute detail how someone dies of a heart attack, but we do not know the complete breakdown of all the chemical compounds found in garlic or what makes up 85% of...

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Chemistry of skin: Desquamation

When your skin cells reach the top layer of the stratum corneum, they will sit there for about 14 days before sloughing off. This process is called desquamation or exfoliation. Interestingly enough, there is so much scientists don’t know about this process. Scientists know there are enzymes that will break the bonds between the corneocytes,...

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Chemistry of skin: An overview (updated)

I know I wrote a post of this nature last year, but I thought it was time to write a more detailed series of posts on the chemistry of our skin if we’re going to take a look at formulating for different skin types. Your skin is composed of three layers – the epidermis, the...

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